1) Emphasize FAIR – CL does amazing work with it
a. Computationally derived markers uses the structure to group annotations together
b. Controversial – starting point
2) Problem statement: Classical definition of cell types have properties, classify according to properties, but, transcriptomic cell types, hierarchies do not fully correspond to classical properties. This will increase with multi omics stuff
3) Fly – morpho as basis,
4) RNAseq is not only thing, but broader, scRNAseq is a good example
1) Emphasize FAIR – CL does amazing work with it a. Computationally derived markers uses the structure to group annotations together b. Controversial – starting point 2) Problem statement: Classical definition of cell types have properties, classify according to properties, but, transcriptomic cell types, hierarchies do not fully correspond to classical properties. This will increase with multi omics stuff 3) Fly – morpho as basis, 4) RNAseq is not only thing, but broader, scRNAseq is a good example