How to deal with antisense transcripts

sheynkman-lab / biosurfer

"Surf" the biological network, from genome to transcriptome to proteome and back to gain insights into human disease biology.

MIT License

0 stars 0 forks source link

How to deal with antisense transcripts #15

Open gsheynkman opened 3 years ago

gsheynkman commented 3 years ago

https://github.com/sheynkman-lab/biosurfer/blob/aba9107f9d6c58d5fbad2bc6961d86c694b4532e/isomodules/isoimage.py#L67-L70

Currently - the isoimage code only takes in same-strand ORFs for plotting. We need to think about what to with antisense transcripts, which are prevalent in our long-read data, as well as GENCODE.