sheynkman-lab / biosurfer

"Surf" the biological network, from genome to transcriptome to proteome and back to gain insights into human disease biology.
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Word for alternative 5' end with/without start codon #60

Closed gsheynkman closed 3 years ago

gsheynkman commented 3 years ago

Need a word for this situation: image

gsheynkman commented 3 years ago

Case in which #203 includes the first exon of #202.

The example above - would be alternative 5' end (TSS) leading to alternative start codons.

If the second isoform had the #202 first exon, then what would it be? It wouldn't be an altTIS, becuase those are cases in which the two intiator codons are included in the transcript.

jsaquing commented 3 years ago

right now we're calling this "upstream alternative TIS revealed by alt. TSS" -- may revisit after feedback from collaborators