huangyh09
commented
3 years ago It is heterozygous genotype, and there are often imbalance in the expression of the two alleles, which refers to the "allele frequency" and has different meaning in population genomics.
对于之前的提问，感谢您的快速回答，这里还有另外一个问题：我想知道的是，为什么会在单个细胞中鉴定ＳＮＰ会有等位基因频率一说呢，不应该是在一个群体中鉴定ＳＮＰ的时候才存在等位基因频率？ 对于一个基因来说，我以为突变了之后，所有的ＲＮＡ转录出来的序列都应该是在该位置有突变。 还是说这个ＡＤ有其他的含义呢？
For the previous question, thank you for your quick answer. Here is another question: I would like to know why there is allele frequency in the identification of SNP in a single cell. It should not be the allele frequency when identifying SNP in a population? For a gene, I think that after mutation, all RNA transcripts should have mutations at this location. Or does this ＡＤ have other meanings?