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smith-chem-wisc / MetaMorpheus

Proteomics search software with integrated calibration, PTM discovery, bottom-up, top-down and LFQ capabilities
MIT License
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Add leucine to chymotrypsin cleavage motifs #2336

Closed trishorts closed 4 months ago

trishorts commented 5 months ago

I found an omission in the list of motifs digested by chymotrypsin. This PR fixes that omission and tests that it results in finding chymotrypsin digested peptides ending in Leucine.

image https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/protein-biology/protein-labeling-and-modification/chymotrypsin

codecov[bot] commented 5 months ago

Codecov Report

All modified and coverable lines are covered by tests :white_check_mark:

Comparison is base (15627fc) 92.63% compared to head (5c506ef) 92.68%.

Additional details and impacted files [![Impacted file tree graph](https://app.codecov.io/gh/smith-chem-wisc/MetaMorpheus/pull/2336/graphs/tree.svg?width=650&height=150&src=pr&token=m0HXyK8tFy&utm_medium=referral&utm_source=github&utm_content=comment&utm_campaign=pr+comments&utm_term=smith-chem-wisc)](https://app.codecov.io/gh/smith-chem-wisc/MetaMorpheus/pull/2336?src=pr&el=tree&utm_medium=referral&utm_source=github&utm_content=comment&utm_campaign=pr+comments&utm_term=smith-chem-wisc) ```diff @@ Coverage Diff @@ ## master #2336 +/- ## ========================================== + Coverage 92.63% 92.68% +0.05% ========================================== Files 136 136 Lines 21302 21302 Branches 2924 2924 ========================================== + Hits 19733 19744 +11 + Misses 1095 1086 -9 + Partials 474 472 -2 ``` [see 2 files with indirect coverage changes](https://app.codecov.io/gh/smith-chem-wisc/MetaMorpheus/pull/2336/indirect-changes?src=pr&el=tree-more&utm_medium=referral&utm_source=github&utm_content=comment&utm_campaign=pr+comments&utm_term=smith-chem-wisc)