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smith-chem-wisc / MetaMorpheus

Proteomics search software with integrated calibration, PTM discovery, bottom-up, top-down and LFQ capabilities
MIT License
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Calibration for TMT-labeled samples is needed #267

Open trishorts opened 7 years ago

trishorts commented 7 years ago

can't do it. I have some good data that would certainly benefit from calibration.

trishorts commented 7 years ago

Maybe allow allow peptides with a single fixed mod as calibrants. That way you don't have to use peptides with both tag and carbamidomethyl, etc. Those should be reliable and prevalent.

stefanks commented 7 years ago

This can't be just for fixed mods! What about the case with some other labeling where the masses at the peptide termini could be different. Isn't this also a common case? Nevermind!

stefanks commented 7 years ago

Fixed in https://github.com/smith-chem-wisc/MetaMorpheus/pull/290

trishorts commented 5 years ago

calibration of TMT currently crashes (~version 295/296)