Strategy: For BAM format reads that are reversed in the BAM file are now reverse complemented and their quality score string is reversed immediately, which should prevent issues related to strand. Initial tests show this working for both quality scores and nucleotide distributions.
Strategy: For BAM format reads that are reversed in the BAM file are now reverse complemented and their quality score string is reversed immediately, which should prevent issues related to strand. Initial tests show this working for both quality scores and nucleotide distributions.