A Snakemake workflow for calling small and structural variants under any kind of scenario (tumor/normal, tumor/normal/relapse, germline, pedigree, populations) via the unified statistical model of Varlociraptor.
Adding plotting mutational signatures using siglasso.
Mutational signatures are plotted by subsampling over minimum allele frequencies applying a stepsize of 0.1.
Signatures identified in a subsample are weighted higher when being identified in following subsample with higher minimum allele frequency.
Adding plotting mutational signatures using siglasso. Mutational signatures are plotted by subsampling over minimum allele frequencies applying a stepsize of 0.1. Signatures identified in a subsample are weighted higher when being identified in following subsample with higher minimum allele frequency.