snijderlab / stitch

Template-based assembly of proteomics short reads for de novo antibody sequencing and repertoire profiling
MIT License
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Force germline on low DOC #234

Open douweschulte opened 1 year ago

douweschulte commented 1 year ago

Allow the user to specify that on low DOC positions the germline should be taken instead of the consensus sequence. This could also be a more gray definition where the germline has a specific weight attached to it and a sufficiently high scoring option still has preference, but that is left for implementation time.