souhridm
commented
2 years ago The score for the “unaffected no gene overlap” model is 0.496. Also, the DiGePred manuscript has been published in AJHG in September 2021. Please refer to https://www.cell.com/ajhg/fulltext/S0002-9297(21)00318-9 https://pubmed.ncbi.nlm.nih.gov/34529933/
for the updated manuscript.
Thanks
Best regards
Souhrid
PhD candidate Tony Capra lab | Jens Meiler lab Dept. of Biological Sciences | Center for Structural Biology Vanderbilt University | Nashville | TN | USA On Oct 19, 2021, 3:18 PM -0500, arton2008 @.***>, wrote:
Hello, I'm using the DiGePred scores to annotate rare variants. In the Wiki page it is recommended to use "unaffected no gene overlap score" model. What threshold would you suggest for using scores for "unaffected no gene overlap" model ? In the paper 0.53 was suggested for Digenic score. Should we use the same score for "unaffected no gene overlap" model?
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ghost
Hello, I'm using the DiGePred scores to annotate rare variants. In the Wiki page it is recommended to use "unaffected no gene overlap score" model. What threshold would you suggest for using scores for "unaffected no gene overlap" model ? In the paper 0.53 was suggested for Digenic score. Should we use the same score for "unaffected no gene overlap" model?