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sqjin / CellChat

R toolkit for inference, visualization and analysis of cell-cell communication from single-cell data
GNU General Public License v3.0
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Downregulated genes in different celltypes #610

Open Imm123 opened 1 year ago

Imm123 commented 1 year ago

Hi, I was wondering if it is possible to extract downregulated genes if I am analyzing communication between cellA and cellB? Apparently, the function subsetcommunication is only used in different conditions (e.g., health and disease) and same celltype (e.g, skincells), or am I wrong?

Thanks for the help

sqjin commented 1 year ago

@Imm123 We have example codes for identifying downregulated signaling when comparing different conditions. One way you can do is to filter the interactions based on your differential analysis