sstadick / perbase

Per-base per-nucleotide depth analysis
MIT License
115 stars 13 forks source link

[feature] Base Quality Filter and BGZIP support #38

Closed sstadick closed 3 years ago

sstadick commented 3 years ago

This adds support for an optional min-base-quality flag for base-depth that adds a cutoff check for each base. If the base quality for a base is less than the cutoff than the base is recorded as an N instead of as an [A, C, T, G].

Additionally this adds support for bgzipping the output. It does not yet automatically index the bgzipped output.

Lastly, this updates dependencies to latest version and updates the README to stay in sync with the commands options. It also adds a much needed changelog.