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stat-lab / MOPline

Detection and genotyping of structural variants
MIT License
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haploid genomes #8

Closed mmpust closed 9 months ago

mmpust commented 9 months ago

Thanks for developing and sharing MOPline! Are there options to use this with prokaryotes/haploid genomes? Thanks, Marie

stat-lab commented 9 months ago

There are no options to be used for prokaryotes/haploid genomes. Even for haploid genome, MOPline would genotype most SVs to homozygous genotypes but several to heterozygous SVs. Because such heterozygous SVs are likely to be low quality ones in the haploid genome, these should be validated in the downstream analysis whether these are true or false.

mmpust commented 9 months ago

Thank you for the quick response!