statgen / METAL

Meta-analysis of genomewide association scans
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P VALUE META ANALYSIS, are duplicate markers from multiple studies not accepted? #27

Closed ymberzal closed 1 year ago

ymberzal commented 1 year ago

I am conducting a p value based meta analysis with GWAS summary statistics collected from over 30 studies. Some studies have reported the same SNPs, and I included those in my input file along with their direction, p value and sample weight (which is different for each study). This is what i get -

WARNING: Invalid p-values for 8 other markers also ignored

WARNING: An additional 87 rows with duplicate marker names were ignored

Does METAL not accept same markers from multiple studies with a different p value and N?