Open dqq0404 opened 4 months ago
When the reference genome updates from hg19 to hg38, all given rsIDs for SNPs remain unchanged. The update only "updates" the coordinates of existing SNPs, adds information to newly discovered SNPs and assigns them new rsIDs.
I used liftover to convert GRCh38 to GRCh37, but the SNP id keep the same. Do I have to continue using the transformed coordinates to match to the SNP id of the GRCh37? I randomly searched the SNP ids corresponding to several converted coordinates on NCBI and found that the snp ids did not change, so I am not sure whether the two versions only changed the location information while the SNP ids did not change.