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statgen / pheweb

A tool to build a website to browse hundreds or thousands of GWAS.
MIT License
154 stars 65 forks source link

add support for 'pval_is_neglog10' config option #207

Closed MatthewMaher closed 5 months ago

MatthewMaher commented 1 year ago

regenie is a newish very popular GWAS tool. However, its output files do not contain P-vals, but rather -log10(P-vals). Thus preprocessing of the files is necessary on the way to pheweb. This change adds a new config option that will apply the needed transformation of -log10 pvals, removing the need for an extra step.

abought commented 1 year ago

Apologies for the delayed response. A teammate has been working with PheWeb recently, and she and I can look over this PR for feedback when we both return from PTO. Thanks for contributing!