statisticalbiotechnology / diffacto

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feature suggestion: rescale intensities to preserve TIC #3

Closed timosachsenberg closed 6 years ago

timosachsenberg commented 6 years ago

Would it make sense to scale the quantities in the output to match the original TIC?

percolator commented 6 years ago

In a sense, the output from diffacto is already scaling with the TIC, i.e. its a weighted geometrical mean of the TICs of the informative peptides. In your mind, which TIC would you scale to? The TIC of the most abundant peptide?

On Thu, Jan 25, 2018 at 10:40 AM, Timo Sachsenberg <notifications@github.com

wrote:

Would it make sense to scale the quantities in the output to match the original TIC?

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timosachsenberg commented 6 years ago

Ah ok sorry, my bad - that's exactly what we want. I guess I misunderstood a quick chat we had about the result file.