stefpeschel / NetCoMi

Network construction, analysis, and comparison for microbial compositional data
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How to interpret SPRING correlation values? #84

Closed antonkratz closed 1 year ago

antonkratz commented 1 year ago

Is there a way to intuitively interpret SPRING values? I note that the vast majority of the american gut microbiome example data is somewhere between -0.1 and 0.2.

What are the possible extrema?

The values seem somehow low?! Does this mean that in the example data the OTUs do not correlate much according to SPRING?

muellsen commented 1 year ago

Hi Anton, the original SPRING publication is here: https://www.frontiersin.org/articles/10.3389/fgene.2019.00516/full The values are essentially partial correlation coefficients (so are in the interval [-1,1]. So, here, from the small subset of American Gut (a few hundred samples) there are only small partial correlation estimated...