Closed stas-malavin closed 5 months ago
Thank you for reaching out. Nucleotide sequences are enough to build a DB. Metabuli translates it to build DB. You cannot specify the translation table. The standard table is utilized for all. Since it handles metagenomic data, query reads have to be translated with standard codons. To best match the query, reference DB is also built using standard table.
Metabuli DB and MMseqs2 DB are different.
Thanks again!
From: Stas Malavin @.> Sent: Tuesday, May 21, 2024 5:02:21 PM To: steineggerlab/Metabuli @.> Cc: Subscribed @.***> Subject: [steineggerlab/Metabuli] Question regarding databases (Issue #65)
Hi,
Could you please clarify—to build a database, do I need both nt and aa seqs, or does metabuli translate nucleotides by itself? If it translates, can I specify the translation table?
And the databases themselves are not MMSeqs2 databases, right?
Thank you
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Thanks for the elaborated reply!
Hi,
Could you please clarify—to build a database, do I need both nt and aa seqs, or does metabuli translate nucleotides by itself? If it translates, can I specify the translation table?
And the databases themselves are not MMSeqs2 databases, right?
Thank you