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stephenslab / mashr

An R package for multivariate adaptive shrinkage.
https://stephenslab.github.io/mashr
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can mashr be used in interaction terms #109

Open arkyl opened 2 years ago

arkyl commented 2 years ago

Hi, We were estimating association difference in a variable, by interaction term in linear model, in multiple tissues. I am wondering if the mashr can be used in beta and sd of the interaction term, for meta analysis of association difference in multiple tissues. Thanks a lot! Yue

pcarbo commented 2 years ago

@arkyl Yes, if you have estimates (and se's) of the interaction effect in multiple tissues mashr should be suitable for this analysis. (I'm not quite sure about the meta analysis part.)

arkyl commented 2 years ago

Thanks very much for the quick reply! The meta analysis here simply means mashr analysis.