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stephenslab / susieR

R package for "sum of single effects" regression.
https://stephenslab.github.io/susieR
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What pre-processing are required for SusieR? We don't need to remove LD but it looks like we need to centre our data? #204

Open garyzhubc opened 11 months ago

garyzhubc commented 11 months ago

What pre-processing are required for SusieR? We don't need to remove LD but it looks like we need to centre our data?

garyzhubc commented 11 months ago

Both genotype and phenotype need to be standardized, am I right?

pcarbo commented 11 months ago

@garyzhubc If you are using the susie function, for example, there is no need; the susie function includes options to center (intercept = TRUE) and/or standardize.