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stschiff / msmc2

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minimum covergae for running MSMC2 #34

Closed AliceIob closed 3 years ago

AliceIob commented 3 years ago

Hello, I was wondering what's the minimum sequencing coverage required for running MSMC and getting reliable results. I have sequence data with coverage 3-5X, is that enough?

Thanks

stschiff commented 3 years ago

Hi.

Not really. See here: https://link.springer.com/protocol/10.1007%2F978-1-0716-0199-0_7 https://link.springer.com/protocol/10.1007/978-1-0716-0199-0_7

Best, Stephan

On 7. Oct 2021, at 10:07, AliceIob @.***> wrote:

Hello, I was wondering what's the minimum sequencing coverage required for running MSMC and getting reliable results. I have sequence data with coverage 3-5X, is that enough?

Thanks

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