QC about TSS.enrichment and nucleosome_signal

[siqi-zZ]

Hello,

I have a question, I found our sample have low scATAC-seq library quality. can I change filter value? like stander is pbmc <- subset( x = pbmc, subset = nCount_peaks > 3000 & nCount_peaks < 30000 & pct_reads_in_peaks > 15 & blacklist_ratio < 0.05 & nucleosome_signal < 4 & TSS.enrichment > 3 ) pbmc

can I change like this for got more fregments? pbmc_donor1 <- subset( x = pbmc_donor1, subset = nCount_peaks > 3000 & nCount_peaks < 50000 & pct_reads_in_peaks > 15 & blacklist_ratio < 0.05 & nucleosome_signal < 1 & # nucleosome_signal < 4 & TSS.enrichment > 1 # TSS.enrichment > 3
) The attachement is my sample before QC. Wati for respond and thinks for useful package!!!!