swolock / scrublet

Detect doublets in single-cell RNA-seq data
MIT License
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scATAC data #10

Open TheSallyGardens opened 4 years ago

TheSallyGardens commented 4 years ago

Hi there, Thanks for a great tool! Can I use this tool to predict the data of scATAC?

swolock commented 4 years ago

Hi @TheSallyGardens,

I haven't worked with scATAC-seq data and am not very familiar with the standard approaches for its analysis. I think that Scrublet's basic strategy could be used to predict doublets in scATAC-seq data, but it would probably require some modifications (e.g., in normalization, feature filtering, and decomposition).

Is there a standard analysis package that you use to analyze scATAC-seq data?

TheSallyGardens commented 4 years ago

Hi @TheSallyGardens,

I haven't worked with scATAC-seq data and am not very familiar with the standard approaches for its analysis. I think that Scrublet's basic strategy could be used to predict doublets in scATAC-seq data, but it would probably require some modifications (e.g., in normalization, feature filtering, and decomposition).

Is there a standard analysis package that you use to analyze scATAC-seq data?

Thank you for your answer.I'm also looking for this kind of software.