tanlongzhi / dip-c

Tools to analyze Dip-C (or other 3C/Hi-C) data
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Generating 3D proximity map and visualization of TAD #56

Open Xuyuch opened 1 year ago

Xuyuch commented 1 year ago

Hi @tanlongzhi Thanks for your powerful Dip-c tools. I am looking for a way to generate a 3D proximity map like the one you mentioned in your article.

A 3D proximity map—a matrix of fractions of cells where each pair of 20-kb particles are nearby in 3D (distance ≤ 3.0 radiiwas then generated by binarizing each single-cell matrix of pairwise 3D distances and averaging them, with “scripts/threshold_np_float.py” of the “dip-c” package (“scripts/threshold_np_float.py 3”).

And I did not find such scripts in the files. I guess it may be moved to somewhere else. Could you please tell me where it is? Thank you.

Also, I am trying to figure out the TADs in single cells and I saw TAD.py in this file. Is the output file of dip-c tad-l shows the exact region of TAD regions? And is there a way to visualize such a TAD result file? Any information or guidance is really appreciated. Thank you.

Yuchen