tanlongzhi / dip-c

Tools to analyze Dip-C (or other 3C/Hi-C) data
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Calculating radius of a given nucleus #58

Open carliemcgrath opened 1 year ago

carliemcgrath commented 1 year ago

Hi @tanlongzhi ! I'm looking to visualize the distance from a given allele and the periphery of the nucleus. However, I'm not sure how to find the radius of each nucleus. Taking the most extreme x, y and z value away from the center would likely overestimate the shape, as I imagine most nuclei are not perfectly spherical and may have some protrusions. Perhaps filtering out those extremes would be helpful. Perhaps calculating the radius of gyration of the nucleus would be a decent representation of the real radius. What are your thoughts? How would you go about finding the radius of each nucleus? Thank you!!!