tanlongzhi / dip-c

Tools to analyze Dip-C (or other 3C/Hi-C) data
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merge .allValidPairs of the same celltype cells to reconstructe 3D model #64

Open zcq23 opened 2 months ago

zcq23 commented 2 months ago

Hi Tan@tanlongzhi, my 3D model aligning between rep1-3 of the single cell sample "SRR25585058_20Kb_1-3.clean.3dg" is: [M::align] median deviation between file 0 and file 1: 0.11901128445530633 [M::align] median deviation between file 0 and file 2: 0.10202856767681674 [M::align] median deviation between file 1 and file 2: 0.30208532515466541

but when I compare the cell with another single cell "SRR25585060_20Kb_1-3.clean.3dg"(which as SRR25585058_20Kb_4-6.clean.3dg, they are the same celltype), the RMSD are: [M::align] median deviation between file 0 and file 3: 24.71208459362338 [M::align] median deviation between file 0 and file 4: 24.71182519219675 [M::align] median deviation between file 0 and file 5: 24.70092361301726

and I have a lot of cells of the same celltype. I wonder whether I can merge them to reconstructe the 3D model to remove the difference between cells, so I can compare their structure differences causing by celltype rather than cell individual.😭 thanks in advance and hope for your reply!!!