hi sir:
there are many indel hotspot discovery in the paper of "Accelerating discovery of functional mutant alleles in cancer" as below:
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We identified 1,165 statistically significant hotspot mutations of which 80% arose in 1 in 1,000 or fewer patients. Of 55 recurrent in-frame indels, we validated that novel AKT1 duplications induced pathway hyperactivation and conferred AKT inhibitor sensitivity.
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but the hotspot soft will Discard the ins and del in soft script.
how can i get indel hotpsot in mydata?
thanks
hi sir: there are many indel hotspot discovery in the paper of "Accelerating discovery of functional mutant alleles in cancer" as below:
================
We identified 1,165 statistically significant hotspot mutations of which 80% arose in 1 in 1,000 or fewer patients. Of 55 recurrent in-frame indels, we validated that novel AKT1 duplications induced pathway hyperactivation and conferred AKT inhibitor sensitivity.
=================
but the hotspot soft will Discard the ins and del in soft script. how can i get indel hotpsot in mydata? thanks