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tdmore-dev / tdmore

In silico evaluation of precision dosing
https://tdmore-dev.github.io/tdmore/dev
GNU Affero General Public License v3.0
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Allow to specify a target function #40

Closed rfaelens closed 3 years ago

rfaelens commented 6 years ago

We should be able to not only target a specific concentration, but a specific individual clinical utility function.

Example include:

  1. Eff=EMax(CONC) and Safety=EMax(CONC). CU = xEff - ySafety. Find the dose at which CU becomes optimal.
  2. fT = Time above target. Find the dose for which fT=70%.

We will start by creating an example using the current API. Based on this example, we will evaluate if more development is needed.

rfaelens commented 6 years ago

Therefore, we also need to specify not only "Find the dose that makes X = Y", but also "Find the dose that maximizes Y"