tdmore-dev / tdmore

In silico evaluation of precision dosing
https://tdmore-dev.github.io/tdmore/dev
GNU Affero General Public License v3.0
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Review the design/API for dose selection and recommendation #51

Closed rfaelens closed 3 years ago

rfaelens commented 6 years ago

When designing the dose recommendation API from scratch, I always imagined distinct steps:

  1. Specify the search space: what parameters can we vary? Some are continuous, others are discrete. This defines an n-dimensional space.
  2. Define evaluation criteria for each point in n-dimensional space. This may be 'CONC - TARGET', or may be 'Clinical Utility', 'Cost', etc.
  3. Define 'selection' criteria. Which treatment regimen will you eventually pick or recommend. This is often either "f(X) = Y" or "max f(X)", but may combine several "Y > Z, and max f(X)".

We should evaluate the API we have built so far, and check if it fits the paradigm above.