openNCA computation engine is an R package that provides for generation of pharmacokinetic parameter estimates using non-compartmental (NCA) pharmacokinetic analysis methods.
MIT License
27
stars
5
forks
source link
Provide a mechanism to optionally include/exclude incorporate of CONC<#>, CONCTIME<#> values in parameter results dataset #288
openNCA Computation engine currently doesn't provide any option to prevent incorporation of the CONC<#>, CONCTIME<#> input concentration and time values in the output parameter results dataset.
Concept for controlling this is to implement placeholder parameters in the mct$PARAMETERLIST entries to control incorporation.
CONCT - placeholder parameter name for the CONC1, CONC2, CONC3, etc values
CONCTIMET - placeholder name for the CONCTIME1, CONCTIME2, CONCTIME3, etc values
mct$PARAMETERLIST <- "CMAX;TMAX;AUCLAST;CONCT;CONCTIMET" configuration would include the CONC and CONCTIME values in the resulting parameter dataset with the results from run_computation()
mct$PARAMETERLIST <- "CMAX;TMAX;AUCLAST" configuration would not include the CONC and CONCTIME values in the resulting parameter dataset with the results from run_computation().
openNCA Computation engine currently doesn't provide any option to prevent incorporation of the CONC<#>, CONCTIME<#> input concentration and time values in the output parameter results dataset.
Concept for controlling this is to implement placeholder parameters in the mct$PARAMETERLIST entries to control incorporation.
CONCT - placeholder parameter name for the CONC1, CONC2, CONC3, etc values
CONCTIMET - placeholder name for the CONCTIME1, CONCTIME2, CONCTIME3, etc values
mct$PARAMETERLIST <- "CMAX;TMAX;AUCLAST;CONCT;CONCTIMET" configuration would include the CONC and CONCTIME values in the resulting parameter dataset with the results from run_computation()
mct$PARAMETERLIST <- "CMAX;TMAX;AUCLAST" configuration would not include the CONC and CONCTIME values in the resulting parameter dataset with the results from run_computation().