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tgen
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tempe
A container focused and streamlined iteration of the Phoenix pipeline
GNU General Public License v3.0
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Release v1.2.0
#47
Closed
bryce-turner
closed
1 year ago
bryce-turner
commented
1 year ago
Major changes (Changes that cause restarts are in bold):
All containers have been updated to use a more optimimally sized image, or using the image provided by the authors
We changed base containers over to debian instead of a heavy rockylinux base, also moved to multi-stage builds
Tool updates for bcftools, samtools, htslib, deepvariant, GATK, ichorCNA, sigprofiler, vardict
We have added support for user supplied variables for the variant filtering tasks
New tools added:
CNVear
b_pure
Added PCR Free workflow
https://github.com/tgen/tempe/issues/15
Since alignment must restart,
https://github.com/tgen/tempe/issues/17
is handled
Adjusted support for fasterq files
https://github.com/tgen/tempe/issues/24
Petagene is only loaded for the copy fastq step and is decompressing the fasterq as part of the copy operation
Multiple UMI aware alignment updates
https://github.com/tgen/tempe/issues/25
https://github.com/tgen/tempe/issues/26
https://github.com/tgen/tempe/issues/27
https://github.com/tgen/tempe/issues/36
https://github.com/tgen/tempe/issues/37
Adjusted memory usage for a couple of workflows including lancet and deepvariant
https://github.com/tgen/tempe/issues/33
Deepvariant is using an example of memory request based on the numberOfReads in the sample, this is planned to be expanded upon
Removed workflows that are outdated/superseded by newer tools:
snpEff
singleCellRNA support tasks (these will be broken into a separate pipeline in order to reduce workflow complexity)
lumosVar
CHIP/CutRun alignment and processing
Major changes (Changes that cause restarts are in bold):
All containers have been updated to use a more optimimally sized image, or using the image provided by the authors