Pre-processing for bulk RNA-seq?

theislab / cpa

The Compositional Perturbation Autoencoder (CPA) is a deep generative framework to learn effects of perturbations at the single-cell level. CPA performs OOD predictions of unseen combinations of drugs, learns interpretable embeddings, estimates dose-response curves, and provides uncertainty estimates.

BSD 3-Clause "New" or "Revised" License

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Pre-processing for bulk RNA-seq? #8

Open bitcometz opened 2 years ago

bitcometz commented 2 years ago

hello,

Thanks for this great software CPA.

I want to use it for my bulk RNA-seq after drug treatment.

Could you give some suggestions about Pre-processing for my data? Should I normalized the data first and then format it into h5ad format?

Thanks !!!