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theislab / destiny

R package for single cell and other data analysis using diffusion maps
https://theislab.github.io/destiny/
GNU General Public License v3.0
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Plotting different conditions on the same diffusion components #36

Closed Kensei-K closed 3 years ago

Kensei-K commented 3 years ago

Hi!

I've started to use destiny to analyze sc-RNAseq data where I have WT and a treated sample, and I'm expecting that the treatment will affect the developmental trajectories.

I've used the same set of genes to perform diffusionMap on WT and the treated sample. And I see difference there.

But is there a way to project the treated sample onto diffusion components calculated based on the WT as a reference, for more of a direct comparison?

Thank you in advance!

flying-sheep commented 3 years ago

You mean like here? https://github.com/theislab/destiny/issues/31#issuecomment-654951132

Kensei-K commented 3 years ago

No.

dm_predict does exactly what I wanted to do! I found your answer in one of the other posts.

Thanks!