applying destiny DiffusionMap() to bulk RNA sequencing data

theislab / destiny

R package for single cell and other data analysis using diffusion maps

https://theislab.github.io/destiny/

GNU General Public License v3.0

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applying destiny DiffusionMap() to bulk RNA sequencing data #42

Open taylorreiter opened 3 years ago

taylorreiter commented 3 years ago

Hello, I'm curious if the DiffusionMap() function can be applied to bulk RNA sequencing data counts. Does doing so violate assumptions of normalization/noise control implemented in destiny, or do these methods also work for bulk RNA-seq data?