theislab / ncem

Learning cell communication from spatial graphs of cells
https://ncem.readthedocs.io/
BSD 3-Clause "New" or "Revised" License
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Interpreting Results from NCEM: Obtaining Ligand-Receptor Pairs #164

Open hahia opened 3 months ago

hahia commented 3 months ago

Hello,

After running NCEM, how can I obtain the ligand-receptor pairs for each cell type pair? The sender_effect and receiver_effect analyses only provide the target genes in the pathway "celltypeA ---> ligand ----> receptor ----> target_genes ----> celltypeB".

If NCEM cannot provide this information, could you advise me on a method that can be used to deconvolute spatial transcriptomics (ST) data to achieve this?

Thank you!