Critical bug introduced in #43

timbitz / Whippet.jl

Lightweight and Fast; RNA-seq quantification at the event-level

MIT License

105 stars 21 forks source link

Critical bug introduced in #43 #46

Closed timbitz closed 7 years ago

timbitz commented 7 years ago

Any complex events with edge extension had a bug introduced as of pull request #43 and tag v0.7.1.

Will be fixed by #45.

timbitz commented 7 years ago

Just for documentation, the bug introduced in v0.7.1 allowed edges to be extended without the graphs being reduced, this results in wildly incorrect PSI values for complex events with extended edges being calculated. e.g.

ENSG00000084623.11_1 5 chr1:32691772-32691921 + CE 0.7033 0.099 0.651,0.75 227.0 K3 1.6414 4-5-6:0.4179,6-7:0.2854 4-6:0.0037,4-7:0.0075,6-7:0.2854 4-5:122.0,4-6:1.0,4-7:2.0,5-6:102.0,6-7:153.0