tjbencomo / ngs-pipeline

Pipeline for Somatic Variant Calling with WES and WGS data
MIT License
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Add stringent variant filtering option #65

Closed tjbencomo closed 3 years ago

tjbencomo commented 3 years ago

Add option in the config to use more stringent filtering threshold to retain variants after FilterMutectCalls finishes.

This could be an if statement in combine_mafs.py that would require a minimum depth for every SNV and minimum number of reads for every alternate allele