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tonydisera / gene.iobio

An iobio app for examining gene variants
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Rank variants order #235

Closed AlistairNWard closed 8 years ago

AlistairNWard commented 8 years ago

The ordering of rows for ranking has changed. We should keep ClinVar on top by default, not SnpEff.

tonydisera commented 8 years ago

My rationale is that a high impact variant trumps a moderate variant with clinvar annotations. But you make a valid point. There are so few clinvar variants that they should stand out. Perhaps gene.iobio should only rank only on 'pathogenic' variants and 'likely pathogenic' but not on 'uncertain significance'.

AlistairNWard commented 8 years ago

I thought we were only ranking on pathogenic and likely_pathogenic. If not, yes we should.