transbioZI / Gimpute

An efficient genetic data imputation pipeline
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chipAnnoFile - rs or SNP type #1

Closed HagenC closed 5 years ago

HagenC commented 5 years ago

Hi,

Thank you for developing Gimpute. I looking forward to use you pipeline for imputation and have some questions I hope you can help me with.

I have data from PsycArrayB (37) and read in your instruktions that there are two types of geneotyping chip annotation file: "SNP" and "rs" . PsychChipB is a mix of SNP and rs-numbers.

So my qustion is: is the rs-number used in the imputation or is it enough with position and strand? If the rs-number is used, are the non-rs probes exluded and should I translate as many as possible probeIDs to rs-number and rename the probe IDs?

Cheers, Christian