Adaptive PDR optimization termination

treangenlab / Olivar

Olivar: towards automated variant aware primer design for multiplex tiled amplicon sequencing of pathogens

https://doi.org/10.1038/s41467-024-49957-9

GNU General Public License v3.0

19 stars 2 forks source link

Adaptive PDR optimization termination #11

Open mxwang66 opened 2 months ago

mxwang66 commented 2 months ago

Currently termination is based on reference length and amplicon length. Should based on the distribution of Loss of PDR sets (normal distribution with min/max greater than a threshold).