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trvrb / flux

Integrating influenza antigenic dynamics with molecular evolution
http://bedford.io/papers/bedford-flux/
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Sampling bias in incidence correlation #23

Closed trvrb closed 10 years ago

trvrb commented 11 years ago

Likewise, in Fig. 5, the negative correlation between drift in different clades in each season could, again, be driven by variation in the number of strains per clade that were subjected to HI each season. The authors could rule this out either by simulation or, more simply, be repeating their analysis after subsampling an equal number of isolates per clade each season for inclusion into the BMDS.