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trvrb / flux

Integrating influenza antigenic dynamics with molecular evolution
http://bedford.io/papers/bedford-flux/
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Drift vs P&I mortality #28

Closed trvrb closed 11 years ago

trvrb commented 11 years ago

Does a similar correlation analysis to the one shown in Fig. 4 find a relationship between estimated within-clade antigenic drift and excess P & I mortality attributed to influenza?

trvrb commented 11 years ago

We have begun to extend the correlation analysis between within-clade antigenic drift and multiple measures of influenza incidence, including ILI, virus isolation, excess P&I mortality and influenza-associated hospitalization rates. This analysis is also attempting to look at a finer temporal scale, rather than the course-grained 1-year bins in the current study and attempting to better match geographic bounds in antigenic and incidence data. This said, we believe that further extending the incidence correlation requires a separate publication to describe adequately, and is beyond the scope of the current analysis.