trvrb / flux

Integrating influenza antigenic dynamics with molecular evolution
http://bedford.io/papers/bedford-flux/
12 stars 5 forks source link

Drift vs sampling count correlation #35

Closed trvrb closed 10 years ago

trvrb commented 10 years ago

In the "Punctuated evolution and its epidemiological consequences" section, the part about subsampling to look at whether drift associates with number of isolates should be expanded. I would suggest starting a new paragraph at the current "We test to see..." sentence that briefly explains the rationale for why this test is being done (rationale articulated by other reviewer in original critiques). I also think that it would be nice to have a table or figure somehow representing the actual results of this analysis.

trvrb commented 10 years ago

We've expanded out this sentence to a paragraph following the paragraph on the year-to-year drift vs incidence correlation. We give rationale for the test, explain the bootstrap procedure, give p-values for both combined and separate analyses across lineages and provide a figure showing a scatterplot of the data.