search

trvrb / flux

Integrating influenza antigenic dynamics with molecular evolution
http://bedford.io/papers/bedford-flux/
12 stars 5 forks source link

Vaccine efficacy #39

Closed trvrb closed 10 years ago

trvrb commented 10 years ago

The first paragraph of the Introduction refers to "efficacy against a fixed vaccine formulation to decline over time." Although I understand the point, the wording seems off here. What declines is the efficacy of the fixed vaccine formulation against circulating viruses, not the efficacy against the vaccine formulation.

trvrb commented 10 years ago

We've revised the clause to "antigenic drift causes efficacy of a fixed vaccine formulation against circulating viruses to decline over time."