First draft of frailty analysis -Descriptive

RiazAziz commented 3 years ago

[ ]Send SQL codes for Steve to check - Git Hub
[ ] Produce demographic description of the study population
[ ]- [ ] Outcome : Admission to ICU , for those admitted to ICU ( MV/RRT/Vasopressor support)
[ ] Include a marker for illness severity = NEWS/ APACHE

docsteveharris commented 2 years ago

Issues discussed today

Denominator

up to 900 admissions in 14m; need to see if we can work out why?
- check for duplicates incl visit_occurrence, dates of admission etc
- look for characteristics that might provide a clue: e.g. journey, age, etc
- get a couple of examples and work with Dave R to double check
not enough kids and should exclude
filter all non-ICU out for governance purposes (CCHIC or audit purposes)

Frailty approaches

Polypharmacy definition

working with unique oral meds on admission after some simple exclusions (e.g. anti-emetics, antibiotics that the inpatient might have started)

ICD-10 codes

list from Simon that works
weighted list that is summed to produce score

Co-morbidities

count within a list of custom codes from ICD10 or SNOMED

Validation suggestions

backend to frontend reviews
sense checks e.g. against age
sense checks e.g. correlations between scores

Confounders

NEWS on admission and NEWS on ICU admission
maybe median NEWS on those days

Outcome measure

ventilation ever
RRT ever
hospital mortality
LoS

Nice to do

TEPs and DNACPR

docsteveharris commented 2 years ago

already assembled into (several) single tables including

one row per patient (first in the time period)
one row per admission

so work toward a slide presentation for the lab focus on the cohort building and the features and the checks that have been done for those features then hopefully have a go at running the model before the presentation

and if all going well then use HYLODE ethics to look at how well these features work for whole hospital questions such as ICU admission and frailty

RiazAziz commented 2 years ago

Quality checks

Kids in the database : Total < 18 - 5500

uclhal / Riaz-PhD