ukhsa-collaboration / variant_definitions

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B.1.1.529 Y505H #17

Closed ggrimes closed 2 years ago

ggrimes commented 2 years ago

Why is the amino acid change Y505H is not part of the B.1.1.529 (pentagon-refining.yml) signature?

The website outbreak.info

https://outbreak.info/compare-lineages?pango=B.1.1.7&pango=B.1.177&pango=B&pango=Delta&pango=AY.4.2&pango=Omicron&pango=Kappa&pango=B.1.617.3&gene=S&threshold=75&nthresh=1&sub=false&dark=true

has it in 87.8% of B.1.1.529 sequences and it is also part of the PANGO signature in

https://github.com/cov-lineages/pango-designation/issues/361

Thanks for the great resource,

Graeme