I am running a study with the following information:
-- Father (wild type, unaffected)
-- Child1 (male, proband, affected)
-- Child2 (female, affected)
I'd like to prioritize variants using denovogear and created the following .ped file:
##PEDNG v1.0
#Family Individual Father Mother Sex Phenotype
FAM FAM_a . . male 0
FAM FAM_b FAM_a . male 1
FAM FAM_c FAM_a . female 1
When running denovogear I often get the following message:
BCF Parsing Error! Unable to find trio!
Members missing : {N}
Where N will vary between 1,2 or 3. Is this expected behavior? Why would it say that it was missing for 3 -- does that mean the location just matches the reference genome for all 3 family members?
Hi All,
I am running a study with the following information: -- Father (wild type, unaffected) -- Child1 (male, proband, affected) -- Child2 (female, affected)
I'd like to prioritize variants using denovogear and created the following .ped file:
When running denovogear I often get the following message:
Where N will vary between 1,2 or 3. Is this expected behavior? Why would it say that it was missing for 3 -- does that mean the location just matches the reference genome for all 3 family members?