search

uw-ipd / RoseTTAFold2NA

RoseTTAFold2 protein/nucleic acid complex prediction
MIT License
329 stars 73 forks source link

Antibody structure prediction #117

Open vella12-osu opened 2 months ago

vella12-osu commented 2 months ago

Hello, I am new to the field and have a potentially basic question. I would like to know if a group of antibodies bind to a particular DNA sequence. Is RoseTTAFold2NA able to model antibody structure if I provide sequences for the heavy and light chains? Thank you.

anar-rzayev commented 2 months ago

I think it is possible to test it out. You have a Heavy+Light Chain antibody structure, and you want to test out whether it will bind to the DNA sequence. I might try it out if you are curious about how RF2NA will perform for your particular case.