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vaccineontology / VO

Vaccine Ontology
https://obofoundry.org/ontology/vo.html
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MUC1-KLH Conjugate Vaccine #549

Closed Jusontin closed 1 year ago

Jusontin commented 3 years ago

Vaccine name: MUC1-KLH Conjugate Vaccine Type: Conjugate vaccine Status: Clinical trial Host Species: Human Description: A peptide vaccine, containing human tumor-associated epithelial mucin (MUC1) conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with MUC1-KLH conjugate vaccine may stimulate humoral and cytotoxic T-lymphocyte (CTL) responses against tumor cells expressing the MUC1 antigen. In this vaccine, MUC1 antigen is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition. MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in an aberrant or deglycosylated form in various cancers such as those of the breast, prostate, and ovary. (NCIT_C2232). Immunization Route: n/a PubMed: n/a PumMed Link: n/a Gene/protein: n/a VIOLIN Link: http://www.violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5251&keywords=MUC1-KLH%20Conjugate%20Vaccine

yuanyp19 commented 1 year ago

Added to VO:http://purl.obolibrary.org/obo/VO_0005463 It will be shown in our next VO release.